Before we look at how to manage red blood disorder, let us begin by giving simple clarifications on what disease of the red blood cells entails.
Disorders of the red blood cells (RBCs), the blood cells that carry oxygen from the lungs to every area of the body, are referred to as red blood cell (RBC) disorders. It is crucial to state here that red blood cell abnormalities come in a wide variety of forms.
Anemia is characterized by deficiencies in red blood cell enzymes (such as G6PD), disorders of the red blood cell membrane (such as hereditary spherocytosis), hemoglobinopathies (such as sickle cell disease and thalassemia), hemolytic anemia, nutritional anemias (such as iron deficiency anemia and folate deficiency), disorders of heme production (such as sideroblastic anemia), and finally, hemochromatosis.
When considering the symptoms of Red Blood Cell(RBC) disorders, it is crucial to note that the sort of red blood cell (RBC) issue a child has will determine the symptoms.
Fatigue, lack of energy, a decreased ability to tolerate physical activity, and irritability are some typical general anemia symptoms. Pale lips, skin, and hands are another.
Jaundice, scleral icterus (yellow eyes), an enlarged spleen, and gallstones are additional common signs of hemolysis (increased red blood cell breakdown).
In terms of the causes of RBC Disorders, the majority of RBC diseases are brought on by blood anomalies or mutations. Drugs and specific medical problems might also play a role.
Based on the overall conclusions of a thorough medical history and physical examination, RBC abnormalities may be suspected. A kid’s doctor may request several blood and genetic tests to confirm the diagnosis, depending on the type of RBC disease the child has. Doctors will be able to present the best treatment alternatives once all tests are finished.
In terms of treatment, the type of RBC that is present will determine the course of treatment, which may involve:
✔️Dietary supplements (e.g. iron, folate, vitamin B12)
✔️Splenectomy: spleen removal through surgery
✔️Antibiotics that affect the immune system (e.g. corticosteroids, intravenous immunoglobulin)
✔️Treatment for sickle cell disease with hydroxyurea
✔️Transfusions of blood