Pregnant women may be able to find out if their growing fetus has genetic issues that raise their risk of miscarriage thanks to a new, affordable same-day test.
According to a recent study, the Short-read Transport Rapid Karyotyping (STORK) test can identify additional or missing chromosomes in samples obtained from common prenatal testing, such as chorionic villus sampling and amniocentesis.
Before implantation, the test can also be performed to evaluate in vitro fertilized embryos.
STORK was compared to industry-recognized techniques for genetic analysis by a team at Columbia University Irving Medical Center led by Brynn Levy and Dr. Zev Williams. They examined 218 samples and discovered that STORK had a 98% to 100% accuracy rate.
Another batch of 60 samples showed STORK agreement with results from common clinical testing at a 100% level.
According to researchers, STORK is quicker than the tests now in use, giving answers in hours as opposed to days. Instead of having to send the test to a lab, the test can be performed at the clinic or hospital.
Additionally, it is less expensive, costing less than $50 per sample if 10 are run simultaneously, or up to $200 if one sample is run alone.
The potential value of STORK in determining the genetic reasons for miscarriage was praised by researchers. Genetic testing is now only advised if a woman has experienced several miscarriages, however, a simple and affordable test like STORK can be provided following a single miscarriage.
Researchers stated STORK could speed up IVF by enabling a fast assessment of embryo viability before freezing.
On August 18, they published their research in the New England Journal of Medicine.
The U.S. National Institute of Child Health and Human Development provided the study’s primary funding, and the National Cancer Institute provided supplementary assistance.